We think card-based video games are pretty inherently hilarious on their own, in that they use expensive, cutting-edge electronics to simulate small pieces of paper. There are, of course, advantages to this approach (online play, computer-governed rules) but it's funny on a very fundamental level.
However, when video card games, like Card Hero, include dramatic, action-packed cutscenes in their card game, they leave "inherently hilarious" and buy tickets to LOLlapalooza. The kid in the intro is all screaming and posing and stuff, and crazy lightning effects show up, as if he's going to go have some flying Dragon Ball Z battle or something; when he is, in fact, playing some cards, which is one of the most sedentary things you can do.
Oh, but in general, Card Hero looks pretty neat.